oxaprozin increases levels of neomycin PO by decreasing renal clearance. Avoid or Use Alternate Drug. Minor (1)oxaprozin increases levels of vancomycin by decreasing renal clearance. Modify Therapy/Monitor Closely. Either increases toxicity of the other by Other (see comment). fondaparinux and oxaprozin both increase anticoagulation. Use Caution/Monitor.aspirin and oxaprozin both increase serum potassium. Coadministration may result in a significant decrease in renal function. Modify Therapy/Monitor Closely. pharmacodynamic antagonism. oxaprozin and Siberian ginseng both increase anticoagulation. Monitor Closely (2)oxaprozin decreases effects of nebivolol by pharmacodynamic antagonism. Either increases toxicity of the other by pharmacodynamic synergism. If any of these effects last or get worse, tell your doctor or pharmacist promptly.Remember that this medication has been prescribed because your doctor has judged that the benefit to you is greater than the risk of side effects. Increased risk of upper GI bleeding. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. Monitor Closely (1)oxaprozin decreases effects of alfuzosin by pharmacodynamic antagonism. Either increases effects of the other by pharmacodynamic synergism. Additive antiplatelet effect may occur. oxaprozin, hydrocortisone. Author disclosure: No relevant financial affiliations. Use Caution/Monitor. Use Caution/Monitor. Use Caution/Monitor. Monitor Closely (1)oxaprozin increases and pirbuterol decreases serum potassium. eHealthMe is studying from 2,834 Daypro users for its effectiveness, alternative drugs and more. Individual plans may vary Consult your doctor or pharmacist for more information.This medication may make you more sensitive to the sun. Use Caution/Monitor. oxaprozin will increase the level or effect of sulindac by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown. Comment: Combination may increase risk of bleeding. Either increases toxicity of the other by Other (see comment). Minor/Significance Unknown. Either increases toxicity of the other by pharmacodynamic synergism. unspecified interaction mechanism. Use Caution/Monitor. aspirin/citric acid/sodium bicarbonate and oxaprozin both increase anticoagulation. Use Caution/Monitor. Use Caution/Monitor. Either increases toxicity of the other by pharmacodynamic synergism. Minor/Significance Unknown. Minor/Significance Unknown. Use Caution/Monitor. Monitor Closely (1)rivastigmine increases toxicity of oxaprozin by pharmacodynamic synergism. What is Mobic? Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. Use Caution/Monitor.oxaprozin decreases effects of candesartan by pharmacodynamic antagonism. eltrombopag increases levels of oxaprozin by decreasing metabolism. Either increases toxicity of the other by Other (see comment). Use Caution/Monitor. pharmacodynamic antagonism. oxaprozin decreases effects of telmisartan by pharmacodynamic antagonism. Clomipramine inhib. Either increases toxicity of the other by pharmacodynamic synergism. Coadministration may result in a significant decrease in renal function. Modify Therapy/Monitor Closely. cefadroxil will increase the level or effect of oxaprozin by acidic (anionic) drug competition for renal tubular clearance. Related/similar drugs prednisone, aspirin, ibuprofen, meloxicam, naproxen, Cymbalta, hydroxychloroquine Before taking this medicine Either increases toxicity of the other by pharmacodynamic synergism. Use Caution/Monitor.Minor (1)metolazone will increase the level or effect of oxaprozin by acidic (anionic) drug competition for renal tubular clearance. A collection of Implementing AHRQ Effective Health Care Reviews published in AFP is available at https://www.aafp.org/afp/ahrq. Modify Therapy/Monitor Closely. Warnings Effect of interaction is not clear, use caution. Use Caution/Monitor. Monitor Closely (2)flurbiprofen and oxaprozin both increase anticoagulation. Comment: Combination may increase risk of bleeding. Use Caution/Monitor. Monitor Closely (1)oxaprozin increases and formoterol decreases serum potassium. Effect of interaction is not clear, use caution. Minor/Significance Unknown. Internal Medicine - rheumatology 23 years experience. Either increases toxicity of the other by pharmacodynamic synergism. Modify Therapy/Monitor Closely. Either increases toxicity of the other by pharmacodynamic synergism. Either increases toxicity of the other by Other (see comment). Minor/Significance Unknown. NSAIDs may diminish the antihypertensive effect of ACE inhibitors. Use Caution/Monitor.Minor (1)oxaprozin will increase the level or effect of tolfenamic acid by acidic (anionic) drug competition for renal tubular clearance. For patients with osteoarthritis, duloxetine resulted in a small improvement in short-term pain response, function, and quality of life compared with placebo. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. Minor/Significance Unknown. Use Caution/Monitor. Monitor Closely (1)quinapril, oxaprozin. NSAIDs decrease prostaglandin synthesis. aceclofenac and oxaprozin both increase anticoagulation. Pharmacokinetics. Monitor Closely (1)oxaprozin and tenecteplase both increase anticoagulation. pharmacodynamic antagonism. Minor/Significance Unknown. Monitor Closely (1)sodium sulfate/potassium sulfate/magnesium sulfate increases toxicity of oxaprozin by Other (see comment). Monitor Closely (1)oxaprozin will increase the level or effect of probenecid by acidic (anionic) drug competition for renal tubular clearance. Use Caution/Monitor. Use Caution/Monitor. Either increases toxicity of the other by decreasing renal clearance. nabumetone and oxaprozin both increase serum potassium. Melatonin may decrease prothrombin time. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. sodium sulfate/potassium sulfate/magnesium sulfate increases toxicity of oxaprozin by Other (see comment). Use Caution/Monitor. Comment: May result in renal function deterioration, particularly in elderly or volume depleted individuals. oxaprozin increases and carbenoxolone decreases serum potassium. If your doctor decides that you need to use this medication between 20 and 30 weeks of pregnancy, you should use the lowest effective dose for the shortest possible time. oxaprozin decreases effects of hydralazine by pharmacodynamic antagonism. Minor/Significance Unknown. Monitor patients for symptoms of active or occult gastrointestinal bleeding. Use Caution/Monitor. NSAIDs decrease prostaglandin synthesis. Use Caution/Monitor. Modify Therapy/Monitor Closely. Modify Therapy/Monitor Closely. Either increases toxicity of the other by pharmacodynamic synergism. oxaprozin will increase the level or effect of acyclovir by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown. Long term (>1 wk) NSAID use. Monitor Closely (1)eltrombopag increases levels of oxaprozin by decreasing metabolism. The recipient will receive more details and instructions to access this offer. Effect of interaction is not clear, use caution. serotonin uptake by platelets. oxaprozin increases and terbutaline decreases serum potassium. Increased risk of bleeding with use of ticagrelor and chronic NSAID use. You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood. Long term (>1 wk) NSAID use. Increased risk of GI ulceration. NSAIDs decrease prostaglandin synthesis. Minor/Significance Unknown. latanoprost, oxaprozin. Minor (1)cefamandole will increase the level or effect of oxaprozin by acidic (anionic) drug competition for renal tubular clearance. Aqueous humor bioavailablity of oxaprozin is significantly increased, with a 4-fold greater area under the curve in the inflamed eye vs. the control Bucolo and Maltese (2002). lornoxicam will increase the level or effect of oxaprozin by acidic (anionic) drug competition for renal tubular clearance. Minor/Significance Unknown. Either increases effects of the other by pharmacodynamic synergism. People with chronic neuropathic pain and fibromyalgia reported small short-term improvements in pain and function with certain anticonvulsants and moderate short-term improvement with certain antidepressants. Use Caution/Monitor. A person viewing it online may make one printout of the material and may use that printout only for his or her personal, non-commercial reference. Clopidogrel and NSAIDs both inhibit platelet aggregation. Chronic use of NSAIDs with prasugrel may increase bleeding risk. Monitor Closely (2)aceclofenac and oxaprozin both increase anticoagulation. Minor/Significance Unknown. pharmacodynamic antagonism. Minor/Significance Unknown. Minor/Significance Unknown. AHRQs summary is accompanied by an interpretation by an AFP author that will help guide clinicians in making treatment decisions. Minor/Significance Unknown. oxaprozin and reteplase both increase anticoagulation. There are conflicting reports from studies of either increased or decreased IOP when ophthalmic prostaglandins are coadministered with NSAIDs (either systemic or ophthalmic). Minor/Significance Unknown. Either increases toxicity of the other by nephrotoxicity and/or ototoxicity. Use Caution/Monitor. Increased risk of GI ulceration. Effect of interaction is not clear, use caution. Monitor Closely (1)oxaprozin and panax ginseng both increase anticoagulation. Use Caution/Monitor. What are the effects of nonopioid drugs on pain, function, and quality of life in patients with specific types of chronic pain, and what are the adverse events related to these drugs? Avoid or Use Alternate Drug. Monitor Closely (1)oxaprozin increases and hydrochlorothiazide decreases serum potassium. Do not increase your dose or take this drug more often than directed. Either increases toxicity of the other by pharmacodynamic synergism. Monitor Closely (1)oxaprozin increases and dopexamine decreases serum potassium. indomethacin and oxaprozin both increase anticoagulation. Increased risk of upper GI bleeding. Avoid concurrent or sequential use to decrease risk for ototoxicity. Use Caution/Monitor. Use Caution/Monitor. Therapeutic duplication ibuprofen and oxaprozin both increase serum potassium. Interaction mainly occurs in preterm infants. oxaprozin increases and bumetanide decreases serum potassium. 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