The efficacy of ERr 731(), a commercially available extract isolated from Rheum rhaponticum, in terms of menopausal complaints like hot flushes, depression, anxiety and vaginal dryness has been proven in a two-year clinical study. Rhubarb supplements have not been approved by the FDA for medical use. Photo by WellnessVerge Cost and Where to Buy Abdominal pain and cramping Uterine contractions Nausea and vomiting [Clinical observation on patients with constipation using Rhubarb and Mangxiao]. Rhubarb (5 10 g, 2 3x/day) given after surgery to stroke patients decreased markers of inflammation (complement 3, complement 4, and hypersensitive C-reactive protein), indicating improved healing [48]. Am J Forensic Med Pathol. Rhubarb rhizome and root are likely safe in the amounts present in food and possibly safe as nutritional supplements, used in adequate amounts. [Nitrogen balance in uremic patients treated with rhubarb retention enema]. Further a recent preclinical study excluded unwanted side effects on the endometrium by showing a lack of stimulation of proliferation marker genes by ERr 731() or its constituents in the 3-day uterotrophic assay. A low dose of Chinese rhubarb (0.75 g/day) was able to reduce the rates of this condition in 333 pregnant women at high risk [43]. Rhubarb has the potential to boost liver function, reduce fatty liver, and improve bile flow alongside conventional treatments. In a clinical trial of 60 people with digestive tract bleeding and fever, taking ground Chinese rhubarb (3 g, 3-4x/day) with ground Chinese ginseng (sanchi powder) boosted recovery. View abstract. View abstract. View abstract. View abstract. Nutrition. One such compound, emodin, is effective against Staphylococcus aureus (even antibiotic-resistant strains), the bacteria that causes staph infections [8]. (Chinese Journal of Modern Developments in Traditional Medicine) 1984;4(2):88-89. Chinese Journal of Nursing 1995;7(30):420-422. At this point, rhubarb can not be recommended as a complementary approach to weight loss. In case you hadnt noticed (fat chance! Bethesda, MD 20894, Web Policies it banned the export of the seeds to block the growing of the plant elsewhere. J Tradit.Chin Med 1997;17(3):168-173. Soybeans and the products produced from them, such as tofu and miso, are a great source of phytoestrogens . Bi, Z. Q. Below is a summary of the existing animal and cell-based studies; they should guide further investigational efforts but should not be interpreted as supportive of any health benefit. Some common varieties of rhubarb include [1, 7+]: The most commonly used parts of the plant for medicinal purposes are the roots and rhizomes, which contain [6, 7+, 3+, 8]: Rhubarb contains toxic compounds known as salts of oxalic acid/oxalates, which are not broken down during cooking. 2015 Mar;12(1):61-9. Would you like email updates of new search results? 2007 Mar-Apr;14(2):270-83. - 1 tbsp flaxseed. 2004;24(12):1084-1086. [Chinese Journal of Modern Developments in Traditional Medicine] 1991;11(7):392-6, 387. Goel, V., Cheema, S. K., Agellon, L. B., Ooraikul, B., and Basu, T. K. Dietary rhubarb (Rheum rhaponticum) stalk fibre stimulates cholesterol 7 alpha-hydroxylase gene expression and bile acid excretion in cholesterol-fed C57BL/6J mice. In the US, you may report side effects to the FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch. A similar trial further confirmed the reductive effect of Siberian rhubarb root on hot flashes over a longer period of time (12 weeks). View abstract. Stimulation of ER has been shown to elicit beneficial estrogen-like activities and reduce adverse side effects. Rhubarb was 89% effective at reducing jaundice, yellowish pigmentation of the skin that indicates bile buildup, in 64 infants [12]. Data suggest that black cohosh has a direct effect on the neurotransmitters and receptors involved in anxiety. Rhubarb will not thrive in a soggy location, where it will be susceptible to root rot, one of the few problems rhubarb can encounter. Estroven contains black cohosh, soy isoflavones, and rhapontic rhubarb extract. Clinical trials used doses ranging from 50 mg to 50 g/day, depending on the disease, type of extract, and other factors. 1996;11(1):186-190. Zhang, W. L. [Treatment of hemorrhage of the upper gastro-intestinal tract with the Chinese drug hai huang san. View abstract. During the time when the female body is not having a menstrual cycle, the body may still be releasing those last few eggs. Its stalk is commonly eaten. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. One can suffer from stomach and intestinal pain, uterine contractions, and watery diarrhea. How It Works Purported Uses and Benefits Do Not Take If Side Effects Special Point Back to top For Healthcare Professionals Scientific Name Clinical Summary Purported Uses and Benefits Mechanism of Action Adverse Reactions Herb-Drug Interactions References Back to top # A B C D E F G H I J K L 10 g/day of Chinese rhubarb in combination with other herbs, stomach washing, and clay, was effective for herbicide poisoning. J Tradit.Chin Med 1993;13(4):249-252. Rhubarb has some mild potential side effects like stomach and intestinal pain, watery diarrhea, nausea, vomiting, rash, and uterine contractions. Because rhubarb has a laxative effect, please discuss with your doctor before taking it with any medications. Stay up to date with the latest health information from experts/contributors at Consumer Health Digest. In a clinical trial of 232 people, A Chinese herbal medicine containing rhubarb called Danning Pian improved non-alcoholic fatty liver disease symptoms and reduced ALT levels, a marker of liver damage [10]. Li, L. Rheum officinale: a new lead in preventing progression of chronic renal failure. The adverse effects most often reported were hypersensitivity or rash, gastrointestinal problems like bloating and diarrhea, and nervous system problems like headaches. 2009 Jan-Feb;16(1):117-31. Sun, D. A. Quarterly Review of Natural Medicine 1997;unlisted:215. View abstract. A Chinese herbal with rhubarb (Jiangzhuoqinggan) was as effective as the standard drug, irbesartan, at reducing both systolic and diastolic blood pressure [42]. Med Clin (Barc). . View abstract. A traditional Chinese herbal remedy that contains rhubarb (Xin-Ju-Xiao-Gao-Fang) at typical to low doses (10%) helped decrease body weight and insulin resistance in a clinical trial of 140 obese people [55]. A: The recommended dosage is one capsule per day, with a glass of water and with or without a meal. It includes rhaponticin and desoxyrhaponticin, which are able to stimulate estrogen receptors. View abstract. Altern Ther Health Med. It also reduced the need for anti-fever medication [1]. No medical claims are implied in this content, and the information herein is not intended be used for self-diagnosis or self-treatment of any condition. sharing sensitive information, make sure youre on a federal Electronic Code of Federal Regulations. However, the study doesnt reveal crucial details such as sample size [54]. The information contained in this website is provided for general informational purposes only. SSO.Schweiz.Monatsschr.Zahnheilkd. Common Side Effects Most side effects of products containing black cohosh are mild. Is Rhapontic rhubarb the same as black cohosh? View abstract. . Curr Ther Res, Clin Exp 1981;29(3):525-536. The rhaponticin and desoxyrhaponticin mimic estrogen, and so theyre able to stimulate estrogen receptors. Rhubarb is a laxative. Journal of Chinese Materia Medica 1989;14(8):501-3, 512. (Chinese Journal of Modern Developments in Traditional Medicine) 1984;4(10):597-600, 579. [Retention enema with Rheum decoction in treating renal failure]. Zhao D, Feng SX, Zhang HJ, et al. View abstract. Liudvytska O, Ponczek MB, Ciesielski O, Krzyanowska-Kowalczyk J, Kowalczyk M, Balcerczyk A, Kolodziejczyk-Czepas J. Nutrients. Tenner S Baillie J, DeWitt J, Vege SS; American College of Gastroenterology. Combinatorial effects of the phytoestrogen genistein and of estradiol in uterus and liver of female Wistar rats. If you are experiencing night sweats or any other concerning symptoms while taking Estroven Complete or any other supplement, it is recommended that you speak with your healthcare provider for further guidance. Estroven Complete is to treat the symptoms associated with menopause and perimenopause. If you are still not able to upload your proof of purchase, please contact us for further assistance (take a moment to look over the sample bill below). There are special precautions when it comes to taking rhubarb extracts: Not Safe for Kids This herbal medicine is not safe for children because of its high amounts of oxalic acid. There is little scientific evidence that black cohosh has a significant effect on menopause symptoms. Sanada, H. [Study on the clinical effect of rhubarb on nitrogen-metabolism abnormality due to chronic renal failure and its mechanism]. Research suggests there are beneficial compounds in rhubarb that may fight cancer, lower cholesterol, reduce inflammation, lower blood pressure and protect eye and brain health. Li, T. [Rhubarb in the treatment of viral hepatitis and its mechanism of action]. which enables users to obtain detailed information and reports based on their genome. Wan B, Fu H, Yin J, Xu F. Efficacy of rhubarb combined with early enteral nutrition for the treatment of severe acute pancreatitis: a randomized controlled trial. The following are some of the common side effects of this herb. 1994;14(4):230-1, 198. Zhongguo Zhong.Xi.Yi.Jie.He.Za Zhi. I have a brand new unopened box of it and if you would like it text me at 412 265-5865 or email me at